Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969360 | 0.83 | ESR1 (0.33) | ESR1ESR2ACHE | |
| SCHEMBL307621 | 0.70 | ESR1 (0.54) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL21387376 | 0.69 | ESR1 (0.69) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL26435127 | 0.69 | ESR1 (0.69) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL8765620 | 0.68 | HSD11B1 (0.55) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL18403094 | 0.66 | ESR1 (0.60) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL8133227 | 0.66 | OPRM1 (0.61) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL1460712 | 0.65 | — | — | |
| SCHEMBL673904 | 0.65 | ESR1 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 | |
| SCHEMBL673869 | 0.65 | ESR1 (1.00) | ESR1ESR2ACHEALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530663-B1 | Heat sensitive recording material | HODOGAYA CHEMICAL CO LTD (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5240898-A | Colorless, or light-colored, electron donative dyestuff, acidic reactant, binder and arylthionaphthalene compound | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0530663-A1 | Heat sensitive recording material | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |