Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798360 | 0.89 | VDR (0.59) | VDRHDAC6 | |
| SCHEMBL9009931 | 0.89 | VDR (0.59) | VDRHDAC6 | |
| SCHEMBL14544644 | 0.87 | VDR (0.70) | VDRHDAC6 | |
| SCHEMBL1248611 | 0.87 | VDR (0.70) | VDRHDAC6 | |
| SCHEMBL1248608 | 0.87 | VDR (0.70) | VDRHDAC6 | |
| SCHEMBL12513364 | 0.86 | VDR (0.67) | VDR | |
| SCHEMBL12513363 | 0.86 | VDR (0.67) | VDR | |
| SCHEMBL13824922 | 0.85 | VDR (0.66) | VDR | |
| SCHEMBL13824927 | 0.85 | VDR (0.66) | VDR | |
| SCHEMBL13824838 | 0.85 | VDR (0.66) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399438-B2 | 2α-methyl-19-nor-1α-hydroxy-homopregnacalciferol and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399438-B2 | 2α-methyl-19-nor-1α-hydroxy-homopregnacalciferol and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-03-19 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-7745404-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7745404-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7566696-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566696-B2 | Use of calcitonin and calcitonin-like peptides to treat and prevent multiple sclerosis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | DELUCA HECTOR F | 2008-06-19 | — | — | US | disclosed |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | DELUCA HECTOR F | 2008-06-19 | — | — | US | disclosed |
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-10 | — | — | US | disclosed |
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105774-A1 | Administering an appropriate dosage schedule of a bone calcium resorption inhibitor like alendronate and a toxic dose of a vitamin D compounds like 1, alpha 25-dihydroxyvitamin D3 without developing hypercalcemia | CALCA, CALCRL, CYP24A1 | VDR 7/4885HDAC6 3948/4885 |
| US-20080146491-A1 | USE OF CALCITONIN AND CALCITONIN-LIKE PEPTIDES TO TREAT AND PREVENT MULTIPLE SCLEROSIS | CALCA, CALCB, CALCRL | VDR 5/4885HDAC6 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.