SCHEMBL9010137

SCHEMBL9010137

CCCC1(CC)C(=O)c2ccccc2C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.42
CYP2D6 P10635 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.41
ALOX12 P18054 2/20 0.41
RECQL P46063 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
CA7 P43166 1/20 0.41
BACE1 P56817 1/20 0.41
CA9 Q16790 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41
PGR P06401 3/20 0.41
NPSR1 Q6W5P4 3/20 0.40
LMNA P02545 2/20 0.40
KMT2A Q03164 2/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967035 0.87 ALDH1A1 (0.48) ELANECYP2D6ALDH1A1MAPK1ALOX12
SCHEMBL10623075 0.78 MMP2 (0.50) ELANECYP2D6ALDH1A1MAPK1ALOX12
SCHEMBL9182761 0.75 S100A4 (0.44) CYP2D6ALDH1A1MAPK1ALOX12RECQL
SCHEMBL14307230 0.73 CYP2D6 (0.41) CYP2D6ALDH1A1MAPK1ALOX12RECQL
SCHEMBL14307234 0.73 CYP2D6 (0.38) ELANECYP2D6ALDH1A1MAPK1ALOX12
SCHEMBL1617518 0.71 APEX1 (0.53) CYP2D6ALDH1A1MAPK1TSHRPGR
SCHEMBL29370881 0.71 APEX1 (0.53) CYP2D6ALDH1A1MAPK1TSHRPGR
SCHEMBL2632159 0.71 ALDH1A1 (0.46) CYP2D6ALDH1A1MAPK1ALOX12RECQL
SCHEMBL9867937 0.71 APEX1 (0.53) CYP2D6ALDH1A1MAPK1TSHRPGR
SCHEMBL7118969 0.71 TYMS (0.49) CYP2D6ALDH1A1MAPK1CASP1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537808-B1 Photosensitive recording material AGFA GEVAERT NV (BE) 1996-11-06 EP disclosed
US-5306587-A With vinyl nitrile dye as charge transport compound AGFA-GEVAERT, N.V. (BE) 1994-04-26 US disclosed
EP-0537808-A1 Photosensitive recording material AGFA-GEVAERT N.V. (BE) 1993-04-21 EP disclosed