SCHEMBL901018

SCHEMBL901018

COc1cc(O)ccc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
ESR1 P03372 1/20 0.57
ESR2 Q92731 1/20 0.57
MAOB P27338 3/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
CAPN1 P07384 1/20 0.57
PARP1 P09874 1/20 0.57
MAOA P21397 1/20 0.57
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 3/20 0.55
TSHR P16473 1/20 0.55
KDM4E B2RXH2 4/20 0.55
HPGD P15428 2/20 0.55
MAPT P10636 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758262 0.86 MAOB (0.58) ALDH1A1MAOBMEN1KMT2ACAPN1
SCHEMBL27182876 0.85 CDC25B (0.61) ALDH1A1ESR1ESR2MAOBMEN1
Isopeonol SCHEMBL29757918 0.84 MAOB (0.57) ALDH1A1MAOBMEN1KMT2ACAPN1
Isopeonol SCHEMBL3713802 0.84 MAOB (0.57) ALDH1A1MAOBMEN1KMT2ACAPN1
Isopeonol SCHEMBL1376231 0.84 MAOB (0.57) ALDH1A1MAOBMEN1KMT2ACAPN1
SCHEMBL536099 0.84 CA12 (0.55) ALDH1A1MAOBCA12CA1CA2
SCHEMBL14156931 0.84 ESR1 (0.56) ALDH1A1ESR1ESR2MEN1KMT2A
SCHEMBL4115468 0.82 MAOB (0.55) ALDH1A1MAOBMEN1KMT2ACAPN1
Methyl 4-Hydroxy-2-Methoxybenzoate SCHEMBL322895 0.82 CA12 (0.67) ESR1MAOBMEN1KMT2ACAPN1
SCHEMBL9812651 0.82 MAOB (0.51) ALDH1A1ESR1ESR2MAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4477693-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS Korea Research Institute of Chemical Technology (KR) 2024-12-18 EP claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 US claimed
CN-116845483-B Composite diaphragm, preparation method thereof and secondary battery 天津市捷威动力工业有限公司 2023-11-28 CN claimed
WO-2023195794-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS 한국화학연구원 2023-10-12 WO claimed
CN-116845483-A Composite diaphragm, preparation method thereof and secondary battery 天津市捷威动力工业有限公司 2023-10-03 CN claimed
WO-2023121411-A1 ECO-FRIENDLY METHOD FOR DECOLORIZATION AND DEPOLYMERIZATION OF COLORED POLYMER CONTAINING ESTER FUNCTIONAL GROUP 한국화학연구원 2023-06-29 WO claimed
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2022-03-31 US claimed
US-11234975-B2 Levorphanol prodrugs and processes for making and using them KEMPHARM, INC. (US) 2022-02-01 US claimed
US-20200390757-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ALTER DOMUS (US) LLC 2020-12-17 US claimed
EP-2771002-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF Kempharm, Inc. (US) 2014-09-03 EP claimed
EP-2736510-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME Kempharm, Inc. (US) 2014-06-04 EP claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
US-20130150395-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2013-06-13 US claimed
WO-2013063204-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2013-05-02 WO claimed
WO-2013016668-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME KEMPHARM INC. (US) 2013-01-31 WO claimed
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof ALTER DOMUS (US) LLC 2012-06-07 US claimed
CN-102480959-A Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof KEMPHARM INC 2012-05-30 CN claimed
EP-2448407-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF Kempharm, Inc. (US) 2012-05-09 EP claimed
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200390757-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 ALDH1A1 1258/4885ESR1 3275/4885ESR2 2422/4885
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS FGB, NR4A1, CYP2E1 ALDH1A1 105/4885ESR1 733/4885ESR2 149/4885
US-12076316-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 ALDH1A1 1258/4885ESR1 3275/4885ESR2 2422/4885
US-11234975-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 ALDH1A1 1258/4885ESR1 3275/4885ESR2 2422/4885
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF CYP2B6, CYP3A43, CYP2D6 ALDH1A1 160/4885ESR1 719/4885ESR2 1105/4885
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof CYP2B6, CYP3A43, CYP2D6 ALDH1A1 160/4885ESR1 719/4885ESR2 1105/4885
US-20130150395-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF OPRM1, OPRK1, CYP2D6 ALDH1A1 92/4885ESR1 561/4885ESR2 838/4885
US-20220096463-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 ALDH1A1 1258/4885ESR1 3275/4885ESR2 2422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.