Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093810 | 0.78 | RAB9A (0.41) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7373003 | 0.78 | RAB9A (0.41) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7405615 | 0.78 | RAB9A (0.42) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7405620 | 0.78 | RAB9A (0.42) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8200998 | 0.77 | MMP1 (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7377721 | 0.76 | MMP1 (0.43) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9327794 | 0.75 | RAB9A (0.39) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7417056 | 0.74 | PTPN1 (0.43) | SYKKLK7KLK5 | |
| SCHEMBL7298371 | 0.73 | CYP3A4 (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7298375 | 0.73 | CYP3A4 (0.38) | RAB9ACYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019961-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |