Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 17/20 | 0.42 |
| ▸ | CA2 | P00918 | 17/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136161 | 0.89 | KCNH2 (0.49) | KCNH2CA2 | |
| SCHEMBL29575593 | 0.75 | TSHR (0.49) | KCNH2CA2 | |
| SCHEMBL10494760 | 0.75 | KCNH2 (0.49) | KCNH2CA2 | |
| SCHEMBL6527472 | 0.73 | KCNH2 (0.47) | KCNH2CA2 | |
| SCHEMBL9136144 | 0.73 | KCNH2 (0.49) | KCNH2CA2 | |
| SCHEMBL7598191 | 0.72 | SLC7A5 (0.44) | BLMPMP22CA1CA2 | |
| SCHEMBL7596061 | 0.72 | CYP1A2 (0.43) | BLMPMP22CA1CA2 | |
| SCHEMBL29588115 | 0.72 | CYP1A2 (0.43) | BLMPMP22CA1CA2 | |
| SCHEMBL9122751 | 0.72 | CYP1A2 (0.45) | KCNH2BLMPMP22HSD17B10CA1 | |
| SCHEMBL9435308 | 0.71 | TDP1 (0.39) | BLMPMP22CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279307-B2 | Bifunctional chelating agents | ABBOTT LAB (US) | 1996-11-13 | — | — | EP | disclosed |
| US-5227474-A | Complexing with radioactive metals, binding to biologically active molecules for treatment of tumors and diagnostic imaging | ABBOTT LABORATORIES (US) | 1993-07-13 | — | — | US | disclosed |
| US-5057302-A | Stable metal complexes of a substrate having a carboxymethyl arm of a polyaminopolycarboxylate framework; medical diagnosis; immunoassay; radiology; antitumor and anticarcinogenic agents | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |