Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010658 | 0.89 | KCNH2 (0.52) | KCNH2CA2 | |
| SCHEMBL7598191 | 0.83 | SLC7A5 (0.44) | LMNACYP2C19CA2TSHR | |
| SCHEMBL29588115 | 0.83 | CYP1A2 (0.43) | LMNACYP2C19CA2ALDH1A1CYP1A2 | |
| SCHEMBL7596061 | 0.83 | CYP1A2 (0.43) | LMNACYP2C19CA2ALDH1A1CYP1A2 | |
| SCHEMBL10494760 | 0.82 | KCNH2 (0.49) | KCNH2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL9435308 | 0.82 | TDP1 (0.39) | LMNACYP2C19CA2TSHR | |
| SCHEMBL5252487 | 0.82 | TDP1 (0.39) | LMNACYP2C19CA2TSHR | |
| SCHEMBL29575593 | 0.80 | TSHR (0.49) | KCNH2MEN1KMT2ALMNAANPEP | |
| SCHEMBL7668229 | 0.80 | CYP1A2 (0.43) | LMNACYP2C19ALDH1A1CYP1A2TSHR | |
| SCHEMBL6527472 | 0.78 | KCNH2 (0.47) | KCNH2MEN1KMT2ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455332-A | Monoclonal antibody 155h.7; labelled for radioimmunology; tumor imaging agent; cancer marker | BIOMIRA, INC. (CA) | 1995-10-03 | — | — | US | disclosed |
| EP-0596011-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002105-A1 | TRIFUNCTIONAL COMPOUNDS HAVING SPECIFICITY FOR MULTI-DRUG RESISTANT CELLS | HYBRITECH INCORPORATED (US) | 1993-02-04 | — | — | WO | disclosed |
| US-4678667-A | DIAGNOSIS AND THERAPY OF TUMORS | 501 Regents of the University of California (US) | 1987-07-07 | — | — | US | disclosed |