SCHEMBL9010683

SCHEMBL9010683

Oc1ccccc1SCCNS

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.46
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.36
NPC1 O15118 3/20 0.36
RECQL P46063 2/20 0.36
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
P4HB P07237 1/20 0.35
HSD17B10 Q99714 2/20 0.35
POLB P06746 2/20 0.35
ALOX15 P16050 2/20 0.35
HIF1A Q16665 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68951 0.83 HSPA5 (0.46) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2
SCHEMBL9524761 0.77 S100A4 (0.44) EPHX2RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL31359159 0.77 EPHX2 (0.52) EPHX2RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL9808033 0.77 ALDH1A1 (0.52) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2
SCHEMBL10504004 0.75 PTGS2 (0.51) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2
SCHEMBL7758746 0.74 EPHX2 (0.45) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2
SCHEMBL7220999 0.73 EPHX2 (0.43) EPHX2RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL8397211 0.73 LMNA (0.45) EPHX2RAB9ASMN1; SMN2MAPTHPGD
SCHEMBL9840115 0.72 PTGS2 (0.44) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2
SCHEMBL6527867 0.72 EPHX2 (0.43) EPHX2MTNR1AMTNR1BRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352697-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1996-11-20 EP disclosed
US-5206104-A Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-04-27 US disclosed
US-5084367-A Asupport with a photoconductive layer, a resin binder for images, electrostatics FUJI PHOTO FILM CO., LTD. (JP) 1992-01-28 US disclosed
EP-0352697-A2 Electrophotographic photoreceptor FUJI PHOTO FILM CO., LTD. (JP) 1990-01-31 EP disclosed