Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232936 | 0.81 | TNKS (0.49) | AMY1AMEN1KMT2AKDM4EHDAC6 | |
| SCHEMBL29351150 | 0.81 | TNKS (0.49) | AMY1AMEN1KMT2AKDM4EHDAC6 | |
| Ammonia Solution, Strong SCHEMBL9010745 | 0.80 | TNKS (0.48) | AMY1AMEN1KMT2AKDM4EHDAC6 | |
| SCHEMBL3660038 | 0.80 | TNKS (0.48) | AMY1AMEN1KMT2AKDM4EHDAC6 | |
| SCHEMBL14141938 | 0.78 | HDAC6 (0.51) | PTGESAMY1ACA12CA9MEN1 | |
| SCHEMBL2372869 | 0.76 | PTGES (0.51) | PTGESMEN1KMT2AKDM4ECASP1 | |
| SCHEMBL30918933 | 0.70 | LMNA (0.53) | PTGESCA12CA9MEN1KMT2A | |
| SCHEMBL3660037 | 0.69 | GUSB (0.48) | AMY1AKDM4ECYP1A2HPGD | |
| SCHEMBL9010793 | 0.68 | PDE2A (0.47) | MEN1KMT2AKDM4EHSD17B10LMNA | |
| SCHEMBL27960056 | 0.68 | F7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160017402-A1 | Method and apparatus utilizing enzyme substrates producing slow diffusing fluorescent product appearances and chromogens, and use in combination with fast diffusing product appearances | ROTH GEOFFREY N (US) | 2016-01-21 | — | — | US | disclosed |
| US-20120225449-A1 | Method and appraratus utilizing enzyme substrates producing slow diffusing fluorescent product appearances and chromogens, and use in combination with fast diffusing product appearances | ROTH GEOFFREY N (US) | 2012-09-06 | — | — | US | disclosed |
| EP-0641351-B1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES INC (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0641351-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES. | MOLECULAR PROBES INC (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5316906-A | Fluorescent dyes for substrates | MOLECULAR PROBES, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| WO-1993004077-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |