SCHEMBL9010836

SCHEMBL9010836

C=C(C)COC(=O)CCCl

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PAM P19021 2/20 0.34
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199157 0.84
SCHEMBL28658708 0.82 PAM (0.36) PAMADRA2AADRA1AMAPTBLM
SCHEMBL17169822 0.82 PAM (0.50) TDP1PAMMAPT
SCHEMBL1695533 0.80 ALDH1A1 (0.48) PAMMAPT
SCHEMBL5285283 0.78 EGLN1 (0.43) PAMADRA2AADRA1AMAPTBLM
SCHEMBL3504158 0.77 PAM (0.55) TDP1PAMMAPT
SCHEMBL9133055 0.77 PAM (0.41) TDP1PAMADRA2AADRA1AMAPT
SCHEMBL6829993 0.77 MGAM (0.48) HSD17B10TDP1
SCHEMBL3503610 0.75 PAM (0.63) PAMMAPT
SCHEMBL808668 0.75 MEN1 (0.41) PAMBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0243160-B2 Blocked isocyanatocarbonyl group-containing polymers NIPPON PAINT CO LTD (JP) 1996-11-13 EP disclosed
EP-0207621-B1 Functional polymers and their production NIPPON PAINT CO LTD (JP) 1995-04-05 EP disclosed
EP-0630921-A2 Functional polymers and their production NIPPON PAINT CO., LTD. (JP) 1994-12-28 EP disclosed
US-5274062-A An N-(substituted oxalyl)-halopropionamide NIPPON PAINT CO., LTD. (JP) 1993-12-28 US disclosed
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US disclosed
EP-0206544-B1 INSTANTANEOUSLY CURABLE COMPOSITION Nippon Paint Co., Ltd. (JP) 1992-01-08 EP disclosed
US-4970281-A COATINGS, ADHESIVES, MOLDING NIPPON PAINT CO., LTD. (JP) 1990-11-13 US disclosed
US-4956491-A MONOMERS FOR RESINS USED IN COATINGS, ADHESIVES OR MOLDING MATERIALS NIPPON PAINT CO., LTD. (JP) 1990-09-11 US disclosed
US-4914225-A MOLDING MATERIALS, COATINGS, ADHESIVES NIPPON PAINT CO., LTD. (JP) 1990-04-03 US disclosed
US-4816537-A COATINGS, AUTOMOBILES NIPPON PAINT CO., LTD. (JP) 1989-03-28 US disclosed
US-4788256-A PENDANT ISOCYANATOCARBONYL GROUP-CONTAINING ACRYLIC POLYMERS; COATINGS; ADHESIVES; MOLDING MATERIALS NIPPON PAINT CO., LTD. (JP) 1988-11-29 US disclosed
EP-0243208-A2 Acrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
EP-0243207-A2 Alpha-alkylacrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
EP-0207621-A2 Functional polymers and their production Nippon Paint Co., Ltd. (JP) 1987-01-07 EP disclosed
EP-0206544-A2 Instantaneously curable composition Nippon Paint Co., Ltd. (JP) 1986-12-30 EP disclosed
US-3970678-A Organotin mercaptide process CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-07-20 US disclosed