Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.43 |
| ▸ | KDM5C | P41229 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148441 | 0.88 | TSHR (0.52) | PAMLMNAALDH1A1TSHROR51E2 | |
| SCHEMBL6523998 | 0.83 | ADRA2A (0.38) | EGLN1PHF8KDM2AKDM5CKDM6B | |
| SCHEMBL10226184 | 0.82 | LMNA (0.52) | EGLN1PHF8KDM2AKDM5CKDM6B | |
| SCHEMBL17169822 | 0.82 | PAM (0.50) | PAMLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL12551760 | 0.81 | ADRA2A (0.37) | EGLN1PHF8KDM2AKDM5CKDM6B | |
| SCHEMBL30050860 | 0.81 | LMNA (0.41) | EGLN1PHF8KDM2AKDM5CKDM6B | |
| SCHEMBL690361 | 0.80 | EGLN1 (0.38) | EGLN1PHF8KDM2AKDM5CKDM6B | |
| SCHEMBL6829994 | 0.80 | MGAM (0.37) | PAMALDH1A1TSHR | |
| SCHEMBL1695533 | 0.80 | ALDH1A1 (0.48) | PAMALDH1A1TSHRMAPTFFAR3 | |
| SCHEMBL530330 | 0.79 | PAM (0.56) | EGLN1PHF8KDM2AKDM5CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005249-A2 | NANOPARTICLES AND DENDRITIC-POLYMER-BASED HYDROGELS COMPRISING THEM | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007001926-A2 | LOW-SWELLING HYDROGEL SEALANTS FOR WOUND REPAIR | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| EP-1370249-A4 | NOVEL DENDRITICPOLYMERS AND THEIR BIOMEDICAL USES | UNIV DUKE (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2006031358-A2 | DENDRITIC POLYMERS, CROSSLINKED GELS, AND THEIR USES AS OPHTHALMIC SEALANTS AND LENSES | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2006-03-23 | — | — | WO | disclosed |
| WO-2006031388-A2 | DENTRITIC POLYMERS, CROSSLINKED GELS, AND THEIR USES IN ORTHOPEDIC APPLICATIONS | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2006-03-23 | — | — | WO | disclosed |
| US-20040131582-A1 | Novel dendritic polymers and their biomedical uses | DUKE UNIVERSITY | 2004-07-08 | — | — | US | disclosed |
| US-20040086479-A1 | Novel dendritic polymers, crosslinked gels, and their biomedical uses | DUKE UNIVERSITY | 2004-05-06 | — | — | US | disclosed |
| EP-1370249-A1 | NOVEL DENDRITICPOLYMERS AND THEIR BIOMEDICAL USES | DUKE UNIVERSITY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002067908-A1 | NOVEL DENDRITIC POLYMERS AND THEIR BIOMEDICAL USES | DUKE UNIVERSITY (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040086479-A1 | Novel dendritic polymers, crosslinked gels, and their biomedical uses | DCLRE1A, ILK, PLOD3 | EGLN1 1644/4885PHF8 3336/4885KDM2A 1018/4885 |
| US-20040131582-A1 | Novel dendritic polymers and their biomedical uses | DCLRE1A, CD14, DDR1 | EGLN1 1636/4885PHF8 4203/4885KDM2A 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.