Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037922 | 0.76 | ALDH1A1 (0.36) | DUSP3PTPN5PTPN11ALDH1A1KDM4E | |
| SCHEMBL7168417 | 0.73 | ALDH1A1 (0.34) | DUSP3PTPN5PTPN11ALDH1A1KDM4E | |
| SCHEMBL612167 | 0.73 | ALDH1A1 (0.34) | DUSP3PTPN5PTPN11ALDH1A1KDM4E | |
| SCHEMBL9010837 | 0.73 | ALDH1A1 (0.35) | DUSP3PTPN5PTPN11ALDH1A1KDM4E | |
| SCHEMBL28308645 | 0.72 | FGFR1 (0.36) | DUSP3PTPN5PTPN11ALDH1A1 | |
| SCHEMBL28275704 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL5616443 | 0.66 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL21356428 | 0.66 | PIK3CG (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL160199 | 0.65 | GDA (0.37) | ALDH1A1 | |
| SCHEMBL8903562 | 0.65 | PIK3CD (0.35) | ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906629-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| US-20070148708-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070148708-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SPR, HPN, SAMHD1 | DUSP3 2000/4885PTPN5 692/4885PTPN11 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.