Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052358 | 0.78 | CTSD (0.46) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL11495804 | 0.76 | L3MBTL1 (0.43) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL11533456 | 0.76 | L3MBTL1 (0.54) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL17600356 | 0.75 | TDP1 (0.52) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL24445380 | 0.74 | LMNA (0.56) | L3MBTL1TSHRALDH1A1CYP2D6SRC | |
| SCHEMBL29392498 | 0.74 | LMNA (0.56) | L3MBTL1TSHRALDH1A1CYP2D6SRC | |
| SCHEMBL4020057 | 0.74 | L3MBTL1 (0.52) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL5565864 | 0.72 | KMT2A (0.47) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL3448887 | 0.72 | L3MBTL1 (0.56) | L3MBTL1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL8974408 | 0.72 | DPP4 (0.50) | ALDH1A1DPP4F2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707480-A | DI-N-SUBSTITUTED AMINO ETHYL ESTERS OF DIPHENYLTHIOACETIC ACID | UNITED PHARMACEUTICALS, INC. (US) | 1987-11-17 | — | — | US | claimed |
| EP-0102554-B1 | COMPOUNDS FOR DILATING THE SMOOTH MUSCLES OF THE UPPER URINARY TRACT | United Pharmaceuticals, Inc. (US) | 1987-04-29 | — | — | EP | claimed |
| EP-0125508-B1 | METHOD FOR STABILIZING A DETRUSOR MUSCLE WHILE INCREASING DETRUSOR MUSCLE STRENGTH | United Pharmaceuticals, Inc. (US) | 1986-10-15 | — | — | EP | claimed |
| EP-0125508-A1 | Method for stabilizing a detrusor muscle while increasing detrusor muscle strength | United Pharmaceuticals, Inc. (US) | 1984-11-21 | — | — | EP | claimed |
| EP-0102554-A1 | Compounds for dilating the smooth muscles of the upper urinary tract | United Pharmaceuticals, Inc. (US) | 1984-03-14 | — | — | EP | claimed |
| US-4432977-A | Method for dilating the smooth muscles of the upper urinary tract | WILLIAM P. POYTHRESS & COMPANY (US) | 1984-02-21 | — | — | US | claimed |
| CN-115698292-A | Aptamers binding to thiamine analogs and derivatives | 梅里特斯英国第二有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-108129370-B | P2Y12 receptor antagonist with nitrile diphenyl thioacetic acid structure and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108129370-B | P2Y12 receptor antagonist with nitrile diphenyl thioacetic acid structure and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108191722-B | P2Y12 receptor antagonist with halogenated diphenyl thioacetic acid structure and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108129369-B | Diphenyl thioacetic acid of P2Y12 receptor antagonist, preparation method and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108191722-B | P2Y12 receptor antagonist with halogenated diphenyl thioacetic acid structure and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-108191722-B | P2Y12 receptor antagonist with halogenated diphenyl thioacetic acid structure and application thereof | 天津小新医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-0125508-A1 | Method for stabilizing a detrusor muscle while increasing detrusor muscle strength | United Pharmaceuticals, Inc. (US) | 1984-11-21 | — | — | EP | disclosed |
| EP-0125508-A1 | Method for stabilizing a detrusor muscle while increasing detrusor muscle strength | United Pharmaceuticals, Inc. (US) | 1984-11-21 | — | — | EP | disclosed |
| EP-0102554-A1 | Compounds for dilating the smooth muscles of the upper urinary tract | United Pharmaceuticals, Inc. (US) | 1984-03-14 | — | — | EP | disclosed |
| EP-0102554-A1 | Compounds for dilating the smooth muscles of the upper urinary tract | United Pharmaceuticals, Inc. (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4432977-A | Method for dilating the smooth muscles of the upper urinary tract | WILLIAM P. POYTHRESS & COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| US-4432977-A | Method for dilating the smooth muscles of the upper urinary tract | WILLIAM P. POYTHRESS & COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| US-4368327-A | REACTION OF CORRESPONDING FURANONE WITH SALT OF THIOCARBOXYLIC ACID | CIBA-GEIGY CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |