Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30346038 | 0.91 | OPRD1 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9011304 | 0.87 | REN (0.58) | PTPN1 | |
| SCHEMBL11108119 | 0.85 | REN (0.46) | OPRD1OPRM1OPRK1PTPN1IL1RN | |
| SCHEMBL9011301 | 0.85 | REN (0.46) | OPRD1OPRM1OPRK1PTPN1IL1RN | |
| Hydrochloric Acid SCHEMBL30346086 | 0.82 | OPRD1 (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12962529 | 0.82 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12962537 | 0.82 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 | |
| SCHEMBL21654224 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9439870 | 0.82 | IL1RN (0.53) | OPRD1OPRM1OPRK1PTPN1IL1RN | |
| Enkephalin SCHEMBL631958 | 0.82 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0110955-B1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIV FLORIDA (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |