Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.58 |
| ▸ | PSMB1 | P20618 | 12/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 12/20 | 0.57 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.57 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.57 |
| ▸ | PSMB10 | P40306 | 7/20 | 0.57 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011201 | 0.88 | PSMB1 (0.59) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL9011324 | 0.87 | OPRD1 (0.59) | PTPN1 | |
| SCHEMBL21430307 | 0.87 | REN (0.65) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL8571242 | 0.87 | PSMB1 (0.61) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL8571238 | 0.87 | PSMB1 (0.61) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL11604023 | 0.86 | CTSS (0.56) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL12706390 | 0.85 | REN (0.68) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL30538832 | 0.85 | REN (0.64) | RENPSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL9011112 | 0.84 | REN (0.66) | REN | |
| SCHEMBL9011111 | 0.84 | REN (0.66) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| EP-0110955-B1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIV FLORIDA (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |
| US-4540564-A | DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0110955-A1 | BRAIN-SPECIFIC DRUG DELIVERY. | UNIV FLORIDA (US) | 1984-06-20 | — | — | EP | disclosed |
| WO-1983003968-A1 | BRAIN-SPECIFIC DRUG DELIVERY | UNIVERSITY OF FLORIDA (US) | 1983-11-24 | — | — | WO | disclosed |