⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15835912 | 0.78 | CARM1 (0.34) | — | |
| SCHEMBL7534186 | 0.77 | PRMT3 (0.42) | — | |
| SCHEMBL476608 | 0.76 | DNM1 (0.40) | — | |
| SCHEMBL2246543 | 0.76 | — | — | |
| SCHEMBL901161 | 0.75 | CARM1 (0.40) | — | |
| SCHEMBL15836053 | 0.75 | KDM4E (0.37) | — | |
| SCHEMBL15833515 | 0.75 | L3MBTL1 (0.40) | — | |
| SCHEMBL15829892 | 0.75 | DNM1 (0.32) | — | |
| SCHEMBL18236755 | 0.75 | KDM4E (0.52) | — | |
| SCHEMBL15835819 | 0.75 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341223-A | Flexible polyurethane foam, preparation method and application thereof | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3294732-B1 | BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | GILEAD SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018138069-A1 | CAPSULES STABILISED BY CATIONIC DISPERSING GROUPS | AGFA NV (BE) | 2018-08-02 | — | — | WO | disclosed |
| US-9951065-B2 | Benzimidazole and imadazopyridine carboximidamide compounds | GILEAD SCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| CN-103987748-B | Use the polyurethane that tertiary amine compound and lewis acidic mixture are prepared as catalyst | 陶氏环球技术有限责任公司 | 2016-09-07 | — | — | CN | disclosed |
| WO-2015165795-A1 | NOVEL TERTIARY DIAMINES OF THE 1,3-DIAMINO-2-PROPANOL FAMILY, PROCESS FOR THE SYNTHESIS THEREOF AND USE THEREOF FOR REMOVING ACIDIC COMPOUNDS FROM A GASEOUS EFFLUENT | IFP Energies Nouvelles (FR) | 2015-11-05 | — | — | WO | disclosed |
| US-6900200-B2 | Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists | WYETH (US) | 2005-05-31 | — | — | US | disclosed |
| EP-1377583-A1 | NOVEL TRICYCLIC HYDROXY CARBOXAMIDES AND DERIVATIVES THEREOF; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Wyeth (US) | 2004-01-07 | — | — | EP | disclosed |
| US-20030018026-A1 | Novel tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
| WO-2002083680-A1 | NOVEL TRICYCLIC HYDROXY CARBOXAMIDES AND DERIVATIVES THEREOF TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH (US) | 2002-10-24 | — | — | WO | disclosed |
| US-4783535-A | Chemical intermediates in the preparation of aromatic-1,4-oxazepinones and thiones | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-11-08 | — | — | US | disclosed |
| US-4610819-A | Process for the preparation of aromatic-1,4-oxazepinones and thiones | A. H. ROBINS COMPANY, INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0175570-A2 | Process for the preparation of aromatic-1,4-oxazepinones and thiones | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1986-03-26 | — | — | EP | disclosed |