Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 5/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.44 |
| ▸ | NMT1 | P30419 | 7/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704401 | 0.84 | KARS1 (0.52) | KARS1PRKD3PRKD1PRKD2DYRK1A | |
| SCHEMBL1704888 | 0.80 | MEN1 (0.50) | KARS1DYRK1AMAPK14 | |
| SCHEMBL901619 | 0.77 | ADORA2B (0.58) | — | |
| SCHEMBL30230278 | 0.75 | ADRB1 (0.59) | KARS1DYRK1ANMT1HRH3CYP1A2 | |
| SCHEMBL1026043 | 0.75 | ADRB1 (0.59) | KARS1DYRK1ANMT1HRH3CYP1A2 | |
| Hydrochloric Acid SCHEMBL31061151 | 0.74 | ADRB1 (0.58) | KARS1DYRK1ANMT1HRH3CYP1A2 | |
| Hydrochloric Acid SCHEMBL20339443 | 0.74 | ADRB1 (0.58) | KARS1DYRK1ANMT1HRH3CYP1A2 | |
| SCHEMBL12685317 | 0.73 | KARS1 (0.60) | KARS1PRKD3PRKD1PRKD2DYRK1A | |
| Hydrochloric Acid SCHEMBL15286384 | 0.72 | KARS1 (0.58) | KARS1PRKD3PRKD1PRKD2DYRK1A | |
| SCHEMBL16716464 | 0.72 | SMO (0.60) | KARS1DYRK1ANMT1TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041476-A1 | PYRIDINE AND ISOQUINOLINE DERIVATIVES AS SYK- AND JAK-KINASE INHIBITORS | ALMIRALL, S.A. (ES) | 2012-04-05 | — | — | WO | disclosed |