Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012507 | 0.90 | NOS1 (0.43) | NOS1ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9012482 | 0.78 | NOS1 (0.38) | NOS1 | |
| SCHEMBL9011965 | 0.76 | NOS1 (0.44) | NOS1ALDH1A1 | |
| SCHEMBL9012049 | 0.71 | NOS1 (0.61) | NOS1 | |
| SCHEMBL4249587 | 0.70 | NOS1 (0.36) | NOS1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8196578 | 0.69 | NOS1 (0.34) | NOS1 | |
| SCHEMBL8199304 | 0.68 | NOS1 (0.34) | NOS1 | |
| SCHEMBL4566478 | 0.66 | NOS1 (0.46) | NOS1ALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL22612236 | 0.66 | ELANE (0.37) | NOS1 | |
| SCHEMBL22612237 | 0.66 | ELANE (0.37) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |