Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249587 | 0.86 | NOS1 (0.36) | NOS1CTSK | |
| SCHEMBL4249589 | 0.86 | NOS1 (0.36) | NOS1CTSK | |
| SCHEMBL9012507 | 0.83 | NOS1 (0.43) | NOS1 | |
| SCHEMBL8196578 | 0.83 | NOS1 (0.34) | NOS1 | |
| SCHEMBL14135 | 0.83 | RAB9A (0.32) | NOS1PCSK9 | |
| SCHEMBL8121 | 0.83 | RAB9A (0.32) | NOS1PCSK9 | |
| SCHEMBL13221 | 0.83 | RAB9A (0.32) | NOS1PCSK9 | |
| SCHEMBL2703386 | 0.83 | NOS1 (0.50) | NOS1CNR2PCSK9 | |
| SCHEMBL24177802 | 0.83 | PCSK9 (0.33) | NOS1PCSK9 | |
| SCHEMBL8199304 | 0.83 | NOS1 (0.34) | NOS1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743320-A2 | Acyl guanidine and amidine prodrugs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |