Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441606 | 0.83 | RIPK1 (0.48) | RIPK1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL9012424 | 0.80 | ADRA2A (0.42) | HTTMAPTSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL9012538 | 0.79 | HDAC1 (0.42) | ALDH1A1HPGDSMN1; SMN2PKMNPC1 | |
| SCHEMBL9012164 | 0.78 | RIPK1 (0.44) | RIPK1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL9011898 | 0.76 | NPC1 (0.34) | NPC1RAB9A | |
| SCHEMBL9012295 | 0.76 | TXN (0.35) | KMT2AHTTMAPTMEN1HPGD | |
| SCHEMBL9222793 | 0.73 | RIPK1 (0.48) | RIPK1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL9012326 | 0.69 | TAAR1 (0.41) | KMT2AALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL9012172 | 0.69 | TAAR1 (0.35) | ALDH1A1HPGDMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9012305 | 0.68 | HDAC1 (0.40) | KMT2AALDH1A1HPGDSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8109390-A | — | — | None | — | — | JP | disclosed |
| JP-H08109390-A | PERFUME COMPOSITION | T HASEGAWA CO LTD | 1996-04-30 | — | — | JP | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |