Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960836 | 0.76 | HSD11B1 (0.44) | HPGDUSP2HSD17B10CALM1POLB | |
| SCHEMBL23860295 | 0.76 | HSD11B1 (0.44) | HPGDUSP2HSD17B10CALM1POLB | |
| SCHEMBL18550001 | 0.75 | CALM1 (0.39) | ALDH1A1MT-CO2ALOX5CALM1LTA4H | |
| SCHEMBL15743127 | 0.74 | DDB1 (0.42) | CALM1LTA4HPOLBHSD11B1 | |
| SCHEMBL6586984 | 0.71 | CALM1 (0.52) | CALM1LTA4HPOLBHRH3 | |
| SCHEMBL1829180 | 0.71 | CALM1 (0.52) | CALM1LTA4HPOLBHRH3 | |
| SCHEMBL2051544 | 0.71 | CALM1 (0.52) | CALM1LTA4HPOLBHRH3 | |
| SCHEMBL8065016 | 0.69 | MAPT (0.40) | ALDH1A1HPGDMT-CO2ALOX5MAPT | |
| SCHEMBL7837228 | 0.69 | MAPT (0.40) | ALDH1A1HPGDMT-CO2ALOX5MAPT | |
| SCHEMBL6275122 | 0.69 | MAPT (0.40) | ALDH1A1HPGDMT-CO2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534700-B1 | Process for cycloalkyl substitution of hydrogen containing silanes | DOW CORNING (US) | 1996-11-20 | — | — | EP | disclosed |