Dimethyl 4-Nitrophenyl Phosphate

Dimethyl 4-Nitrophenyl Phosphate

SCHEMBL901276

COP(=O)(OC)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
ACHE P22303 2/20 0.68
BCHE P06276 1/20 0.68
ALDH1A1 P00352 3/20 0.67
HSD17B10 Q99714 3/20 0.67
MAPK1 P28482 3/20 0.67
CYP3A4 P08684 3/20 0.67
LMNA P02545 2/20 0.67
TP53 P04637 1/20 0.67
THRB P10828 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
CES2 O00748 1/20 0.62
CES1 P23141 1/20 0.62
TSHR P16473 2/20 0.53
POLB P06746 1/20 0.49
APP P05067 1/20 0.46
HSPB1 P04792 1/20 0.46
MAPT P10636 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411255 0.96 CA1 (0.68) CA1CA2ACHEBCHEALDH1A1
SCHEMBL35319 0.88 CA1 (0.71) CA1CA2ACHEBCHEALDH1A1
SCHEMBL2040097 0.85 CA1 (0.67) CA1CA2ACHEBCHEALDH1A1
SCHEMBL25931268 0.84 ALDH1A1 (0.65) CA1CA2ACHEBCHEALDH1A1
SCHEMBL18476332 0.83 CA1 (0.61) CA1CA2ACHEBCHEALDH1A1
SCHEMBL960787 0.82 CES2 (0.80) CA1CA2ACHEBCHEALDH1A1
SCHEMBL8427162 0.82 ALDH1A1 (0.63) CA1CA2ACHEBCHEALDH1A1
SCHEMBL1763157 0.81 CA1 (0.63) CA1CA2ACHEBCHEALDH1A1
SCHEMBL959287 0.81 CA1 (0.63) CA1CA2ACHEBCHEALDH1A1
SCHEMBL10410659 0.81 CA1 (0.63) CA1CA2ACHEBCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186608-A1 NANODIAMONDS AS DELIVERY PLATFORM FOR OXIME ANTIDOTES TO CENTRAL NERVOUS SYSTEM IN ORGANOPHOSPHATE POISONING TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2025-06-12 US claimed
US-20250114653-A1 COMPOSITIONS, METHODS, AND ARTICLES COMPRISING COCAINE ESTERASE FOR DETOXIFYING AN ORGANOPHOSPHATE-BASED AGENT FOUR WINDS BIOTHERAPEUTICS, INC. 2025-04-10 US claimed
CN-119413783-A Methyl paraoxon detection test strip based on oxygen vacancy-ceria and preparation method thereof 吉林大学 2025-02-11 CN claimed
CN-119375378-A Analysis and identification method for semi-volatile organic compounds in human serum sample 华中科技大学 2025-01-28 CN claimed
CN-118681601-B ZrCu-MOG material for cascade degradation of organophosphorus nerve agents and preparation method and application thereof 重庆师范大学 2025-01-24 CN claimed
CN-117586525-B Metal organic framework material based on tetraphenylethane tetracarboxylic acid, and preparation method and application thereof 江苏师范大学 2024-08-23 CN claimed
EP-4373927-A2 COMPOSITIONS, METHODS, AND ARTICLES COMPRISING COCAINE ESTERASE FOR DETOXIFYING AN ORGANOPHOSPHATE-BASED AGENT Four Winds Biotherapeutics, Inc. (US) 2024-05-29 EP claimed
CN-118084969-A Organophosphorus pesticide albumin adduct, preparation method and application thereof, organophosphorus pesticide poisoning detection reagent or kit 山西医科大学 2024-05-28 CN claimed
CN-117920352-A Preparation method and application of zirconium-based MOF (metal oxide fiber) enzyme-like catalytic membrane 河北工业大学 2024-04-26 CN claimed
CN-117797667-A Preparation method and application of cross-linked enzyme aggregate biocatalytic membrane 河北工业大学 2024-04-02 CN claimed
CN-102680589-A Method for determining pesticide residue in ginseng by liquid chromatography-tandem mass spectrometry SHANGHAI INST FOR FOOD AND DRUG CONTROL 2012-09-19 CN claimed
WO-2012041965-A1 PROCESS FOR PRODUCING DIALKYLPHOSPHOTRIESTERS OF NUCLEOSIDES BY ENZYMATIC TRANSESTERIFICATION AND DEPROTECTION THEREOF FOR PRODUCING NUCLEOSIDE MONOPHOSPHATES UNIVERSIDAD NACIONAL DE QUILMES (AR) 2012-04-05 WO claimed
CN-101942062-A Surface imprinted polymer for catalyzing degradation of organophosphorus pesticide and preparation method thereof UNIV NANKAI 2011-01-12 CN claimed
EP-1611246-B1 MEDIUM FOR THE DETECTION AND IDENTIFICATION OF MICRO-ORGANISMS BIOMERIEUX SA (FR) 2010-06-02 EP claimed
US-7691601-B2 Medium for detecting and/or identifying of microorganisms BIOMERIEUX (FR) 2010-04-06 US claimed
CN-101334409-A Methyl paraoxon enzyme-linked immunosorbent assay method UNIV JIANGNAN (CN) 2008-12-31 CN claimed
WO-2008141436-A1 METHOD FOR THE DETECTION AND/OR DETOXIFICATION OF COMPOUNDS UNIVERSITY OF GUELPH (CA) 2008-11-27 WO claimed
CN-1888059-A Recombinat acetylcholinesterase and its prepn process and usage in detecting presticide residue UNIV SHANGHAI JIAOTONG (CN) 2007-01-03 CN claimed
US-20060257966-A1 Medium for detection and identification of micro-organisms BIOMERIEUX (FR) 2006-11-16 US claimed
US-5510247-A ROTATABLE CHEMICAL REACTOR CONTAINING A WATER IN OIL EMULSION HAVING CATALYST IN FIRST PHASE AND LIQUID TO BE REMOVED THROUGH OUTLET IN THE SECOND PHASE; EXTRACTION, ENZYMATIC BIODEGRADATION UNIVERSITY OF PITTSBURGH (US) 1996-04-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186608-A1 NANODIAMONDS AS DELIVERY PLATFORM FOR OXIME ANTIDOTES TO CENTRAL NERVOUS SYSTEM IN ORGANOPHOSPHATE POISONING ACHE, BCHE, DDT CA1 128/4885CA2 183/4885ACHE 1/4885
US-20250114653-A1 COMPOSITIONS, METHODS, AND ARTICLES COMPRISING COCAINE ESTERASE FOR DETOXIFYING AN ORGANOPHOSPHATE-BASED AGENT CES2, BCHE, ACHE CA1 556/4885CA2 1568/4885ACHE 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.