Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.80 |
| ▸ | CES1 | P23141 | 1/20 | 0.80 |
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223704 | 0.89 | CES1 (1.00) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL11588705 | 0.87 | CES1 (0.96) | CES2CES1CA1CA2ALDH1A1 | |
| Water SCHEMBL9045475 | 0.87 | CES1 (0.96) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL11588711 | 0.87 | CES1 (0.96) | CES2CES1CA1CA2ALDH1A1 | |
| Bromide SCHEMBL11420868 | 0.87 | CES1 (0.96) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL609222 | 0.84 | CES1 (0.83) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL233887 | 0.83 | CES2 (0.86) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL5246741 | 0.83 | CES1 (0.86) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL2040099 | 0.83 | CES2 (0.80) | CES2CES1CA1CA2ALDH1A1 | |
| SCHEMBL4823833 | 0.83 | CES2 (0.80) | CES2CES1CA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12510908-B2 | Integration of metal-organic frameworks on textile fibers and fabrics for the destruction of nerve agents under ambient humidity conditions | NORTHWESTERN UNIVERSITY (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250333849-A1 | SOLVENT-BASED COMPOSITIONS AND RELATED METHODS FOR MOLYBDENUM ETCHING | ENTEGRIS INC (US) | 2025-10-30 | — | — | US | disclosed |
| WO-2023209532-A1 | RECOMBINANT PLASMID VECTORS, METHOD FOR PRODUCING ENZYMES THAT HYDROLYZE ORGANOPHOSPHATE, CARBAMATE, AND PYRETHROID INSECTICIDES, AND THE FORMULATION OF SUCH ENZYMES AS FUNCTIONAL COMPONENTS | BIOM CO., LTD. (TH) | 2023-11-02 | — | — | WO | disclosed |
| US-20230048741-A1 | INTEGRATION OF METAL-ORGANIC FRAMEWORKS ON TEXTILE FIBERS AND FABRICS FOR THE DESTRUCTION OF NERVE AGENTS UNDER AMBIENT HUMIDITY CONDITIONS | DEFENSE THREAT REDUCTION AGENCY, US DOD | 2023-02-16 | — | — | US | disclosed |
| WO-2021113296-A1 | INTEGRATION OF METAL-ORGANIC FRAMEWORKS ON TEXTILE FIBERS AND FABRICS FOR THE DESTRUCTION OF NERVE AGENTS UNDER AMBIENT HUMIDITY CONDITIONS | NORTHWESTERN UNIVERSITY (US) | 2021-06-10 | — | — | WO | disclosed |
| WO-2017035253-A1 | METHODS AND COMPOSITIONS FOR PROTEIN PURIFICATION AND ENZYME REACTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-02 | — | — | WO | disclosed |
| US-8722956-B2 | Kit for decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2014-05-13 | — | — | US | disclosed |
| EP-1613402-B1 | METHOD OF DECOMPOSING ORGANOPHOSPHORUS COMPOUNDS | UNIV KINGSTON (CA) | 2013-01-16 | — | — | EP | disclosed |
| US-20110253580-A1 | Method of Decomposing Organophosphorus Compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-10-20 | — | — | US | disclosed |
| US-7875739-B2 | Detoxification of hazardous materials; rapid lanthanum ion catalyzed alcoholysis | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2011-01-25 | — | — | US | disclosed |
| US-20070299275-A1 | Method of decomposing organophosphorus compounds | BROWN R S | 2007-12-27 | — | — | US | disclosed |
| US-7214836-B2 | Method of decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2007-05-08 | — | — | US | disclosed |
| US-6846654-B1 | Catalytic antibodies as chemical sensors | IGEN INTERNATIONAL, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20040230082-A1 | Method of decomposing organophosphorus compounds | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-11-18 | — | — | US | disclosed |
| US-5763249-A | Antibody-mediated reduction of α-ketoamides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0362304-B1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | IGEN INC (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1993012144-A1 | ANTIBODY-MEDIATED REDUCTION OF α-KETOAMIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0362304-A4 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | — | 1991-04-10 | — | — | EP | disclosed |
| EP-0362304-A1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES. | IGEN INC (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1989005977-A1 | CHEMICAL SENSORS EMPLOYING CATALYTIC ANTIBODIES | IGEN, INC. (US) | 1989-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299275-A1 | Method of decomposing organophosphorus compounds | ACHE, L3MBTL3, L3MBTL4 | CES2 84/4885CES1 923/4885CA1 141/4885 |
| US-20040230082-A1 | Method of decomposing organophosphorus compounds | ACHE, L3MBTL3, L3MBTL4 | CES2 84/4885CES1 923/4885CA1 141/4885 |
| US-12510908-B2 | Integration of metal-organic frameworks on textile fibers and fabrics for the destruction of nerve agents under ambient humidity conditions | H1-10, ACHE, H1-4 | CES2 300/4885CES1 646/4885CA1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.