Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806655 | 0.86 | TRPC6 (0.53) | LMNAHPGDNOTUMSMPD1HDAC1 | |
| SCHEMBL20594032 | 0.85 | LMNA (0.49) | LMNAHPGDNOTUMP4HTMGABRP | |
| SCHEMBL30680302 | 0.85 | LMNA (0.49) | LMNAHPGDNOTUMP4HTMGABRP | |
| SCHEMBL1782909 | 0.78 | HPGD (0.72) | LMNAHPGDSMPD1HDAC1HDAC8 | |
| SCHEMBL6079823 | 0.78 | LMNA (0.50) | LMNAHPGDNOTUMHDAC1HDAC8 | |
| SCHEMBL9012949 | 0.77 | TRPC6 (0.52) | LMNAHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1202469 | 0.76 | ALOX5 (0.54) | LMNAHPGDLCKP4HTMGABRA1 | |
| SCHEMBL1973836 | 0.76 | P4HTM (0.73) | LMNAHPGDP4HTMGABRA1GABRG2 | |
| SCHEMBL2492361 | 0.76 | POLB (0.52) | LMNAP4HTMGABRA1GABRG2GABRB3 | |
| SCHEMBL18031337 | 0.76 | TRPC6 (0.45) | LMNAHPGDNOTUMGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532354-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5401734-A | MICROBIOCIDES | FUJISAWA PHAMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5244890-A | Treatment of infectious diseases | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0345671-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |