Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 9/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014134 | 0.89 | CASP6 (0.51) | CASP6GFERACACBCYP4F2CYP4A11 | |
| SCHEMBL23410150 | 0.84 | GPR119 (0.61) | — | |
| SCHEMBL8259410 | 0.83 | GFER (0.59) | CASP6GFERACACBHRH3 | |
| SCHEMBL6539208 | 0.82 | GFER (0.57) | CASP6GFERACACBHRH3 | |
| SCHEMBL9013886 | 0.80 | CASP6 (0.53) | CASP6GFERCYP4F2CYP4A11NAMPT | |
| SCHEMBL16220677 | 0.80 | EPHX2 (0.56) | CYP4F2CYP4A11NAMPTHRH3 | |
| SCHEMBL9013888 | 0.79 | FFAR4 (0.42) | AKR1C3ACACBNAMPTHRH3 | |
| SCHEMBL2096831 | 0.79 | EPHX2 (0.55) | ACACBCYP4F2CYP4A11NAMPT | |
| Hydrochloric Acid SCHEMBL9014030 | 0.79 | CASP6 (0.51) | CASP6GFERCYP4F2CYP4A11NAMPT | |
| SCHEMBL31370640 | 0.79 | ALDH1A1 (0.55) | CYP4F2CYP4A11NAMPTHRH3OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |