Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014131 | 0.82 | HSP90AB1 (0.45) | CHRM3 | |
| SCHEMBL12359570 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2BCHE | |
| SCHEMBL9014105 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ABL1RIN1BCHE | |
| SCHEMBL9014114 | 0.73 | ACHE (0.49) | SMN1; SMN2ABL1RIN1BCHE | |
| SCHEMBL9014112 | 0.71 | OPRK1 (0.53) | SMN1; SMN2ABL1RIN1ALDH1A1 | |
| SCHEMBL4229644 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2BCHEALDH1A1 | |
| SCHEMBL4464631 | 0.70 | BCHE (0.65) | SMN1; SMN2ABL1RIN1BCHECHRM3 | |
| SCHEMBL4135213 | 0.69 | BCHE (0.67) | SMN1; SMN2ABL1RIN1BCHE | |
| SCHEMBL11731487 | 0.68 | SMN1; SMN2 (0.67) | SMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL9380707 | 0.68 | BCHE (0.65) | SMN1; SMN2ABL1RIN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |