Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014140 | 0.81 | HRH1 (0.54) | L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9013903 | 0.81 | SMN1; SMN2 (0.58) | OPRK1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9013996 | 0.81 | KEAP1 (0.49) | LMNAALDH1A1 | |
| SCHEMBL9014111 | 0.79 | ACHE (0.61) | OPRK1SMN1; SMN2LMNAGAAABL1 | |
| SCHEMBL4464631 | 0.78 | BCHE (0.65) | SMN1; SMN2LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL4855546 | 0.78 | HRH3 (0.74) | OPRK1SMN1; SMN2GAAHRH3CARM1 | |
| SCHEMBL8480700 | 0.78 | BCHE (0.55) | SMN1; SMN2LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL1900651 | 0.77 | MAOA (0.48) | SMN1; SMN2LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL10838796 | 0.76 | BCHE (0.47) | SMN1; SMN2LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL11393297 | 0.76 | NPC1 (0.56) | SMN1; SMN2LMNANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |