Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medronic Acid SCHEMBL2383175 | 0.84 | KDM4E (0.59) | ANPEPERAP2GABBR2GABBR1GABRR1 | |
| Phosphoric Acid SCHEMBL9014286 | 0.80 | ALDH1A1 (0.62) | ANPEPERAP2GABBR2GABBR1GABRR1 | |
| Phosphoric Acid SCHEMBL28858109 | 0.80 | ALDH1A1 (0.62) | ANPEPERAP2GABBR2GABBR1GABRR1 | |
| Phosphoric Acid SCHEMBL30680641 | 0.79 | ANPEP (0.50) | ANPEPERAP2GABBR2GABBR1GABRR1 | |
| SCHEMBL5069395 | 0.78 | LMNA (0.56) | ANPEPERAP2ALDH1A1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL3264358 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL28448377 | 0.76 | LAP3 (0.60) | ANPEPERAP2LAP3ALDH1A1ERAP1 | |
| Phosphoric Acid SCHEMBL29275124 | 0.76 | LAP3 (0.60) | ANPEPERAP2LAP3ALDH1A1ERAP1 | |
| SCHEMBL21312 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL28859152 | 0.73 | LAP3 (0.57) | ANPEPERAP2LAP3ALDH1A1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173341-A | Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol | TOKYO ROPE MFG. CO., LTD. (JP) | 1992-12-22 | — | — | US | claimed |
| EP-0470280-B1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MFG CO (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5173341-A | Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol | TOKYO ROPE MFG. CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0470280-A1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MANUFACTURING CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |