Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561519 | 0.84 | CASP1 (0.39) | LMNASMN1; SMN2CYP1A2CASP1NPC1 | |
| Ether SCHEMBL917077 | 0.84 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1NOS1CYP1A2 | |
| 2-Ethoxyethanol SCHEMBL11177096 | 0.81 | ALDH1A1 (0.64) | LMNASMN1; SMN2ALDH1A1NOS1CYP1A2 | |
| Alcohol SCHEMBL8078657 | 0.78 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1CYP1A2CASP1 | |
| SCHEMBL4363406 | 0.78 | TSHR (0.46) | LMNANOS1CYP1A2CASP1TSHR | |
| SCHEMBL12255 | 0.78 | — | — | |
| Ether SCHEMBL9622039 | 0.77 | LMNA (0.37) | LMNASMN1; SMN2ALDH1A1NOS1CYP1A2 | |
| SCHEMBL736034 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2ALDH1A1CYP1A2CASP1 | |
| SCHEMBL10908182 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2ALDH1A1CYP1A2CASP1 | |
| SCHEMBL1011368 | 0.75 | CDK1 (0.37) | LMNACYP1A2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470280-B1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MFG CO (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5173341-A | Coating wire with triazine-thiol derivative, drawing wire thorugh bath, polymerizing triazine-thiol | TOKYO ROPE MFG. CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0470280-A1 | Method for manufacturing polymeric coated steel wires for rubber reinforcement | TOKYO ROPE MANUFACTURING CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |