Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678327 | 0.82 | CYP3A4 (0.47) | KMT2ACYP3A4ALDH1A1HPGDTSHR | |
| SCHEMBL1079613 | 0.75 | CYP3A4 (0.41) | LMNAKMT2AMEN1BLMTDP1 | |
| SCHEMBL8385938 | 0.74 | LMNA (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7463571 | 0.74 | CYP3A4 (0.74) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL1493085 | 0.73 | CYP3A4 (0.40) | CYP3A4ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL17868845 | 0.73 | CYP3A4 (0.40) | KMT2AMEN1TDP1CYP3A4ALDH1A1 | |
| SCHEMBL11015523 | 0.73 | MAOA (0.53) | KMT2AMEN1CYP3A4ALDH1A1HPGD | |
| SCHEMBL17868852 | 0.73 | HPGD (0.50) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL17868849 | 0.73 | CYP3A4 (0.40) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL17868847 | 0.73 | CES2 (0.43) | LMNAKMT2AMEN1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523495-A | REACTING KETONE OR ALDEHYDE WITH A DIHALOPROPENE IN PRESENCE OF ZINC POWDER, WATER AND ACID YIELDS A HALOALLYLCARBINOL WHICH CAN BE DEHALOGENATED WITH A BASE, NONEXPLOSIVE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5258529-A | Dehydrohalogenation of corresponding alkene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-02 | — | — | US | disclosed |