Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014894 | 0.94 | DRD2 (0.52) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL9014893 | 0.93 | HRH3 (0.50) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL9014904 | 0.91 | HRH3 (0.49) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL9014901 | 0.85 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3DRD2DRD3 | |
| SCHEMBL9014685 | 0.80 | DRD3 (0.57) | SLC6A2SLC6A4DRD2DRD3HTR1A | |
| SCHEMBL9014823 | 0.79 | HRH3 (0.43) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL9014815 | 0.79 | KCNH2 (0.55) | SLC6A2SLC6A4DRD2DRD3HTR1A | |
| SCHEMBL9014676 | 0.78 | HTR1A (0.47) | SLC6A2SLC6A4DRD3HTR1AHRH3 | |
| SCHEMBL9014858 | 0.78 | KCNH2 (0.57) | DRD2DRD3HTR1AHTR2ADRD1 | |
| SCHEMBL9014715 | 0.77 | HTR1A (0.43) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578596-A | TREATMENT OF SEROTONERGIC NEURON RELATED DISEASES, MOTION SICKNESS, ANXIXETY, DEPRESSION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0668276-A1 | 2-ALKOXY-5,6,7,8-TETRAHYDROQUINOXALINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-08-23 | — | — | EP | disclosed |