Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16143757 | 0.88 | USP2 (0.40) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL5376216 | 0.88 | NPC1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL9851995 | 0.87 | L3MBTL1 (0.50) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10518597 | 0.84 | L3MBTL1 (0.42) | RAB9AHPGDSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11035938 | 0.83 | MAPT (0.54) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL10509749 | 0.79 | NPC1 (0.35) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL7660067 | 0.78 | LMNA (0.37) | HPGDSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9015526 | 0.76 | MAPT (0.33) | RAB9AHPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9851959 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9378936 | 0.75 | LMNA (0.36) | HPGDSMN1; SMN2TSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510320-A | EXCELLENT CONTROL OF BLACKGRASS AND WILD OATS AND OTHER WEEDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0610314-A1 | HERBICIDAL TRIAZOLECARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993021164-A1 | HERBICIDAL TRIAZOLESULFONATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-10-28 | — | — | WO | disclosed |