Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015529 | 0.87 | NPC1 (0.51) | L3MBTL1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16143757 | 0.86 | USP2 (0.40) | L3MBTL1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10518597 | 0.84 | L3MBTL1 (0.42) | L3MBTL1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL11035938 | 0.81 | MAPT (0.54) | L3MBTL1MEN1KMT2AHTTRAB9A | |
| SCHEMBL9851959 | 0.78 | SMN1; SMN2 (0.43) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10877559 | 0.78 | TRPM8 (0.41) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL10509749 | 0.77 | NPC1 (0.35) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7660067 | 0.76 | LMNA (0.37) | L3MBTL1NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9725533 | 0.75 | TDP1 (0.32) | ALDH1A1LMNASMN1; SMN2HPGDTDP1 | |
| SCHEMBL5376216 | 0.75 | NPC1 (0.52) | L3MBTL1NPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3099066-A | — | — | None | — | — | JP | disclosed |
| JP-H0399066-A | SUBSTITUTED CARBAMOYLTRIAZOLE | BAYER AG | 1991-04-24 | — | — | JP | disclosed |
| EP-0422369-A2 | Substituted carbamoyltriazoles | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |