Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877559 | 0.79 | TRPM8 (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9851995 | 0.78 | L3MBTL1 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11035938 | 0.76 | MAPT (0.54) | SMN1; SMN2KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL9725531 | 0.76 | TDP1 (0.32) | SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL9725533 | 0.76 | TDP1 (0.32) | SMN1; SMN2ALDH1A1LMNATDP1 | |
| SCHEMBL10509749 | 0.75 | NPC1 (0.35) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9015529 | 0.75 | NPC1 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7660067 | 0.74 | LMNA (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL16143757 | 0.74 | USP2 (0.40) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9015526 | 0.72 | MAPT (0.33) | SMN1; SMN2ALDH1A1L3MBTL1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422369-A2 | Substituted carbamoyltriazoles | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |