Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015640 | 0.85 | GPR119 (0.43) | TSHRALOX15ATMTACR1ADAM17 | |
| SCHEMBL8762096 | 0.81 | OPRD1 (0.44) | TSHRALOX15ATMTACR1KDM4E | |
| SCHEMBL7842880 | 0.81 | PKM (0.52) | TSHRALOX15ATMKDM4EPKM | |
| SCHEMBL7840954 | 0.81 | POLB (0.53) | TSHRALOX15KDM4EPOLB | |
| SCHEMBL8762050 | 0.81 | GPR119 (0.44) | TSHRALOX15ATMTACR1KDM4E | |
| SCHEMBL7842738 | 0.80 | POLB (0.45) | TSHRALOX15ATMTACR1KDM4E | |
| SCHEMBL5807947 | 0.79 | HDAC2 (0.45) | TSHRALOX15ATMTACR1ADAM17 | |
| SCHEMBL8762051 | 0.77 | ADORA1 (0.49) | — | |
| SCHEMBL6196117 | 0.75 | TGFBR1 (0.49) | TSHRALOX15ATMADAM17STS | |
| SCHEMBL26523199 | 0.74 | SSTR4 (0.48) | KDM4EPKMGPR119POLBSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576313-A | ENZYME INHIBITORS AND ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-19 | — | — | US | disclosed |