Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915553 | 0.78 | KCNH2 (0.49) | CYSLTR2CYSLTR1ALDH1A1ESR1ADRA2A | |
| SCHEMBL10477134 | 0.77 | RARB (0.56) | THRATHRBALDH1A1HAO1RARB | |
| SCHEMBL902106 | 0.76 | SPHK1 (0.48) | CYSLTR2CYSLTR1ALDH1A1ESR1ADRA2A | |
| SCHEMBL15880521 | 0.75 | KCNH2 (0.44) | CYSLTR2CYSLTR1ALDH1A1ESR1ADRA2A | |
| SCHEMBL13733545 | 0.74 | THRA (0.52) | THRATHRBALDH1A1HAO1RARB | |
| SCHEMBL16915555 | 0.74 | THRB (0.48) | CYSLTR2CYSLTR1THRATHRBALDH1A1 | |
| SCHEMBL2732070 | 0.73 | KCNH2 (0.45) | CYSLTR2CYSLTR1THRATHRBALDH1A1 | |
| SCHEMBL903502 | 0.73 | ESR1 (0.45) | CYSLTR2CYSLTR1ALDH1A1ESR1ADRA2A | |
| SCHEMBL15960543 | 0.73 | ALDH1A1 (0.45) | CYSLTR2CYSLTR1THRATHRBALDH1A1 | |
| Acetic Acid SCHEMBL28904115 | 0.73 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632889-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | Mapi Pharma Limited (IL) | 2013-09-04 | — | — | EP | claimed |
| WO-2012056458-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | MAPI PHARMA LTD. (IL) | 2012-05-03 | — | — | WO | claimed |
| EP-2632889-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | Mapi Pharma Limited (IL) | 2013-09-04 | — | — | EP | disclosed |
| EP-2621886-A1 | PROCESS FOR MAKING FINGOLIMOD | Synthon BV (NL) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012056458-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | MAPI PHARMA LTD. (IL) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012041359-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012041405-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012041707-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON BV (NL) | 2012-04-05 | — | — | WO | disclosed |