Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1B | Q92523 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622241 | 0.85 | CPT1B (0.45) | CPT1BMAPTTP53USP2MEN1 | |
| SCHEMBL11620229 | 0.84 | MEN1 (0.53) | MAPTUSP2MEN1KMT2ACHRM2 | |
| SCHEMBL9015971 | 0.84 | CPT1B (0.70) | CPT1BTP53MEN1KMT2ACHRM2 | |
| SCHEMBL11621143 | 0.84 | MEN1 (0.60) | MAPTUSP2MEN1KMT2ACHRM2 | |
| SCHEMBL9015962 | 0.83 | CPT1B (0.75) | CPT1BMEN1KMT2ACHRM2OPRK1 | |
| SCHEMBL11623951 | 0.83 | L3MBTL1 (0.61) | MAPTMEN1KMT2ACHRM2OPRK1 | |
| SCHEMBL9015980 | 0.82 | CPT1B (0.73) | CPT1BMEN1KMT2ACHRM2OPRK1 | |
| SCHEMBL11622194 | 0.81 | CACNA1G (0.64) | MAPTUSP2MEN1KMT2ALMNA | |
| SCHEMBL9015968 | 0.80 | LMNA (0.47) | CPT1BMAPTTP53MEN1KMT2A | |
| SCHEMBL11618699 | 0.77 | CHRM2 (0.59) | MEN1KMT2ACHRM2OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533579-B1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-12-04 | — | — | EP | disclosed |
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | disclosed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |