Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1B | Q92523 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015962 | 0.96 | CPT1B (0.75) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9015998 | 0.87 | CPT1B (0.93) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9015995 | 0.85 | CPT1B (0.74) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9622223 | 0.85 | CPT1B (0.56) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2885813 | 0.84 | CPT1B (1.00) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9015969 | 0.82 | CPT1B (0.58) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9622863 | 0.81 | CPT1B (0.57) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9015974 | 0.80 | CPT1B (0.73) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9015965 | 0.80 | MEN1 (0.57) | CPT1BMEN1KMT2AKDM4EALDH1A1 | |
| Fumaric Acid SCHEMBL29802140 | 0.78 | CPT1B (0.86) | CPT1BMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | claimed |
| EP-0533579-B1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-12-04 | — | — | EP | disclosed |
| US-5283246-A | Trimetazidine compounds | ADIR ET COMPAGNIE (FR) | 1994-02-01 | — | — | US | disclosed |
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |