SCHEMBL9016030

SCHEMBL9016030

CCCCC(Cl)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.47
ADORA3 P0DMS8 3/20 0.47
SLC6A2 P23975 3/20 0.47
SLC6A3 Q01959 3/20 0.47
LMNA P02545 2/20 0.47
CHRM2 P08172 2/20 0.47
CYP3A4 P08684 2/20 0.47
CHRM1 P11229 2/20 0.47
PTGS1 P23219 2/20 0.47
CYP1A2 P05177 1/20 0.47
PGR P06401 1/20 0.47
AR P10275 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47
DRD1 P21728 1/20 0.47
TBXA2R P21731 1/20 0.47
CYP2C19 P33261 1/20 0.47
ADRA1A P35348 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016024 0.94 ESR1 (0.46) ESR1ADORA3SLC6A2SLC6A3LMNA
SCHEMBL9016039 0.92 ESR1 (0.48) ESR1ADORA3SLC6A2SLC6A3LMNA
Hydrogen Sulfide SCHEMBL11699776 0.91 ESR1 (0.47) ESR1ADORA3SLC6A2SLC6A3LMNA
SCHEMBL7432877 0.88 ESR1 (0.53) ESR1ADORA3SLC6A2SLC6A3LMNA
SCHEMBL28824086 0.82 NPC1 (0.42) SLC6A2SLC6A3SLC6A4
SCHEMBL8973155 0.82 HRH3 (0.45) SLC6A2SLC6A3LMNATDP1SLC6A4
SCHEMBL8973238 0.82 SLC6A2 (0.45) SLC6A2SLC6A3LMNACYP2C9CYP2C19
SCHEMBL28429634 0.80 HTR7 (0.39) SLC6A2SLC6A3LMNACHRM1DRD3
SCHEMBL28771687 0.80 BDKRB2 (0.40) ESR1LMNATDP1ESR2ALDH1A1
SCHEMBL27647959 0.80 CYP1A2 (0.37) LMNACYP3A4CYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103122062-A Solid state polymerization process for polyester with phosphinic acid compounds BASF SE 2013-05-29 CN disclosed
US-5585403-A APPLYING A DICHLOROBENZENE AND A DIALKYLDIMETHYLAMMONIUM HALIDE TO ANIMAL HABITAT TAMURA SEIYAKU KABUSHIKI KAISHA (JP) 1996-12-17 US disclosed