Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19376359 | 0.90 | HTT (0.40) | HRH3HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9397854 | 0.87 | CHRNA7 (0.38) | HRH3CHRNA7ALDH1A1LMNASMN1; SMN2 | |
| Toluene SCHEMBL28304024 | 0.86 | TSHR (0.41) | HRH3CYP17A1ALDH1A1LMNAACHE | |
| SCHEMBL28824086 | 0.83 | NPC1 (0.42) | CYP17A1SMN1; SMN2SLC6A3BDKRB2SLC2A1 | |
| SCHEMBL8973238 | 0.83 | SLC6A2 (0.45) | LMNASMN1; SMN2SLC6A3TDP1SLC6A2 | |
| SCHEMBL28429634 | 0.82 | HTR7 (0.39) | LMNASMN1; SMN2SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28771687 | 0.82 | BDKRB2 (0.40) | HRH3HTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27647959 | 0.82 | CYP1A2 (0.37) | ALDH1A1LMNASMN1; SMN2ALOX5TDP1 | |
| SCHEMBL28017458 | 0.82 | MAPT (0.39) | CYP17A1ALDH1A1LMNASMN1; SMN2SLC6A3 | |
| SCHEMBL9016030 | 0.82 | ESR1 (0.47) | ALDH1A1LMNASLC6A3ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776550-B | C3 and C20 double-esterified glycyrrhetinic acid derivative and preparation method and application thereof | 广东工业大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112375226-B | Bonded amylose derivative and preparation method and application thereof | 苏州纳微科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-112375226-A | Bonded amylose derivative and preparation method and application thereof | 苏州纳微科技股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| EP-0410466-B1 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-5057145-A | PHENYLALKYLIMIDAZOLE COMPOUNDS AS FUNGICIDES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0410466-A2 | Substituted phenylalkylimidazole compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1991-01-30 | — | — | EP | disclosed |