Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016244 | 0.86 | ADRB2 (0.63) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016222 | 0.84 | KCNH2 (0.61) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016231 | 0.83 | MEN1 (0.66) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016229 | 0.80 | HTR2B (0.60) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016250 | 0.79 | KCNH2 (0.59) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016252 | 0.79 | KCNH2 (0.61) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016234 | 0.78 | HTR2B (0.57) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016221 | 0.78 | KCNH2 (0.57) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016253 | 0.77 | KCNH2 (0.59) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL9016210 | 0.77 | KCNH2 (0.59) | ADRB2ADRB1HTR1AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |