Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11522127 | 0.88 | TSHR (0.45) | ACHETSHRGABRA1GABRB2TRPA1 | |
| SCHEMBL8056036 | 0.78 | — | — | |
| SCHEMBL15660504 | 0.77 | TSHR (0.39) | ACHETSHRGABRA1GABRB2ALDH1A1 | |
| SCHEMBL9016372 | 0.77 | TSHR (0.39) | ACHETSHRGABRA1GABRB2ALDH1A1 | |
| SCHEMBL9016332 | 0.76 | TSHR (0.41) | ACHETSHRNPC1RAB9AHSD11B1 | |
| SCHEMBL10955842 | 0.76 | ACHE (0.38) | ACHETSHRGABRA1GABRB2SMN1; SMN2 | |
| Bromide SCHEMBL29017423 | 0.76 | TSHR (0.38) | ACHETSHRGABRA1GABRB2ALDH1A1 | |
| Water SCHEMBL29265399 | 0.76 | TSHR (0.38) | ACHETSHRGABRA1GABRB2ALDH1A1 | |
| SCHEMBL470628 | 0.73 | GABRA1 (0.48) | ACHETSHRGABRA1GABRB2TRPA1 | |
| SCHEMBL11204082 | 0.73 | TSHR (0.45) | ACHETSHRGABRA1GABRB2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683786-B1 | PROCESS FOR THE PREPARATION OF LITHIUM DIARYLPHOSPHIDES AND ALKYLATED DERIVATIVES THEREOF | EASTMAN CHEM CO (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0683786-A1 | PROCESS FOR THE PREPARATION OF LITHIUM DIARYLPHOSPHIDES AND ALKYLATED DERIVATIVES THEREOF. | EASTMAN CHEM CO (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5354894-A | Treating triarylphosphine with lithium and a primary or secondary amine | EASTMAN CHEMICAL COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1994018211-A1 | PROCESS FOR THE PREPARATION OF LITHIUM DIARYLPHOSPHIDES AND ALKYLATED DERIVATIVES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5288912-A | Hydrohalogenation of a triarylphosphine; alkylation; using lithium diarylphosphine as chemical intermediate | EASTMAN KODAK COMPANY (US) | 1994-02-22 | — | — | US | disclosed |