Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011882 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5283277 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL6517024 | 0.83 | TSHR (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2038938 | 0.83 | PKM (0.50) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL26075997 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1554320 | 0.82 | KDM4E (0.53) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL9016430 | 0.81 | USP2 (0.47) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5026445 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL9775462 | 0.80 | TRPA1 (0.47) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL9775463 | 0.80 | TRPA1 (0.47) | ALDH1A1KDM4EMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092045-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2026-04-02 | — | — | US | disclosed |
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| US-12528796-B2 | Modulators of RAS GTPase | TOSK, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4524133-A2 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-3939658-B1 | SUBSTITUTED BENZOPYRROLE AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2024-10-02 | — | — | EP | disclosed |
| US-20240294494-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-09-05 | — | — | US | disclosed |
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |
| US-12043610-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-11866418-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-01-09 | — | — | US | disclosed |
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-0854863-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997003951-A1 | ESTERS AND AMIDES AS PLA2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |
| US-5366984-A | Fungicides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-22 | — | — | US | disclosed |
| WO-1994006737-A1 | PROCESS FOR PREPARING FELBAMATE, 2-PHENYL-1,3-PROPANEDIOL AND INTERMEDIATES | SCHERING CORPORATION (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5294628-A | Fungicides, insecticides, pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| US-5250553-A | Fungicides; pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| US-5166216-A | Fungicides, pesticides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0412763-A2 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | ALDH1A1 2719/4885KDM4E 3382/4885MEN1 2008/4885 |
| US-20240294494-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | C9, C5, C1QBP | ALDH1A1 1047/4885KDM4E 2522/4885MEN1 1641/4885 |
| US-12043610-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | ALDH1A1 1047/4885KDM4E 2522/4885MEN1 1641/4885 |
| US-11866418-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | ALDH1A1 1047/4885KDM4E 2522/4885MEN1 1641/4885 |
| US-20260092045-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | TFPI, F3, BTK | ALDH1A1 3179/4885KDM4E 1536/4885MEN1 1627/4885 |
| US-12528796-B2 | Modulators of RAS GTPase | KRAS, NRAS, HRAS | ALDH1A1 4254/4885KDM4E 3816/4885MEN1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.