Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016422 | 0.94 | PPARG (0.48) | APLNRPPARGACHEPI4KAPI4K2B | |
| SCHEMBL9016396 | 0.91 | APLNR (0.42) | APLNRPPARGACHEPI4KAPI4K2B | |
| SCHEMBL9016524 | 0.91 | PPARG (0.41) | APLNRPPARGACHEAGTR1ESR2 | |
| SCHEMBL9016493 | 0.87 | APLNR (0.42) | APLNRPPARGACHEPI4KAPI4K2B | |
| SCHEMBL9016503 | 0.86 | AGTR1 (0.48) | APLNRPPARGACHEAGTR1AGTR2 | |
| SCHEMBL9016542 | 0.85 | PPARG (0.46) | APLNRPPARGACHEPI4KAPI4K2B | |
| SCHEMBL9016540 | 0.81 | PPARG (0.39) | APLNRPPARGACHEAGTR1ESR2 | |
| SCHEMBL9016423 | 0.81 | PPARG (0.46) | APLNRPPARGACHEPI4KAPI4K2B | |
| SCHEMBL8873865 | 0.81 | AGTR1 (0.47) | ACHEAGTR1AGTR2 | |
| SCHEMBL9016428 | 0.80 | PPARG (0.47) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |