Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.48 |
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016428 | 0.94 | PPARG (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9016415 | 0.91 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9016466 | 0.86 | APLNR (0.44) | AGTR1AGTR2APLNRPPARGACHE | |
| SCHEMBL8872761 | 0.85 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9016493 | 0.83 | APLNR (0.42) | AGTR1AGTR2APLNRPPARGACHE | |
| SCHEMBL9016396 | 0.83 | APLNR (0.42) | AGTR1AGTR2APLNRPPARGACHE | |
| SCHEMBL9016422 | 0.80 | PPARG (0.48) | AGTR1AGTR2APLNRPPARGACHE | |
| SCHEMBL8872013 | 0.79 | AGTR1 (0.46) | AGTR1AGTR2ACHE | |
| SCHEMBL8872834 | 0.78 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL8872253 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |