Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016542 | 0.93 | PPARG (0.46) | PPARGGRIA2GRIA4ESR2NR3C1 | |
| SCHEMBL9016396 | 0.91 | APLNR (0.42) | PPARGGRIA2GRIA4ESR2ACHE | |
| SCHEMBL9016524 | 0.90 | PPARG (0.41) | PPARGGRIA2GRIA4ESR2SLC6A9 | |
| SCHEMBL8878496 | 0.85 | PPARG (0.51) | PPARGAGTR1 | |
| SCHEMBL9016422 | 0.83 | PPARG (0.48) | PPARGGRIA2GRIA4ESR2NR3C1 | |
| SCHEMBL9016411 | 0.83 | SLC6A9 (0.40) | PPARGGRIA2GRIA4ESR2SLC6A9 | |
| SCHEMBL8873723 | 0.82 | ESR2 (0.34) | PPARGESR2NR3C1AGTR1TRPA1 | |
| SCHEMBL9016415 | 0.82 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9016466 | 0.81 | APLNR (0.44) | PPARGESR2ACHEAGTR1APLNR | |
| SCHEMBL8873625 | 0.80 | SLC6A3 (0.47) | ACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |