Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ACR | P10323 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016461 | 0.85 | PPARG (0.36) | PPARGPPARAKMT2APARP10SMN1; SMN2 | |
| SCHEMBL9016500 | 0.83 | PPARG (0.41) | PPARGPPARAKMT2ASMN1; SMN2GAA | |
| SCHEMBL9016505 | 0.83 | PPARG (0.41) | PPARGPPARAKMT2ASMN1; SMN2GAA | |
| SCHEMBL9016533 | 0.78 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL9016432 | 0.78 | MEN1 (0.44) | KMT2AMEN1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL9016470 | 0.74 | CYP3A4 (0.44) | KMT2AMEN1NPC1POLB | |
| SCHEMBL28438921 | 0.69 | PARP10 (0.66) | ADAMTS4KIF11KMT2AMEN1PARP10 | |
| SCHEMBL6284986 | 0.68 | KMT2A (0.64) | ADAMTS4KIF11KMT2AMEN1PARP10 | |
| SCHEMBL731242 | 0.66 | CA1 (0.61) | KIF11KMT2AMEN1PARP10SMN1; SMN2 | |
| SCHEMBL6189783 | 0.66 | ALOX15 (0.52) | KIF11KMT2AMEN1PARP10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |