Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016505 | 0.86 | PPARG (0.41) | PPARGPPARATDP1MAPK1ALDH1A1 | |
| SCHEMBL9016500 | 0.86 | PPARG (0.41) | PPARGPPARATDP1MAPK1ALDH1A1 | |
| SCHEMBL9016513 | 0.85 | ADAMTS4 (0.37) | PPARGPPARAALDH1A1CYP1A2GAA | |
| SCHEMBL9016533 | 0.80 | MEN1 (0.46) | TDP1ALDH1A1CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL9016432 | 0.80 | MEN1 (0.44) | MAPK1ALDH1A1CYP3A4GAASMN1; SMN2 | |
| SCHEMBL9016470 | 0.77 | CYP3A4 (0.44) | CYP3A4KMT2ANPC1POLB | |
| SCHEMBL655457 | 0.70 | CYP1A2 (0.65) | PPARGPPARATDP1ALDH1A1CYP1A2 | |
| SCHEMBL28584562 | 0.70 | CYP1A2 (0.65) | PPARGPPARATDP1ALDH1A1CYP1A2 | |
| SCHEMBL3209492 | 0.68 | PARP10 (0.42) | PPARGPPARATDP1MAPK1ALDH1A1 | |
| SCHEMBL1163280 | 0.66 | PARP10 (0.41) | PPARGPPARATDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |