Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016445 | 0.85 | KMT2A (0.46) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL9016505 | 0.81 | PPARG (0.41) | KMT2ALMNAMAPTNPC1RAB9A | |
| SCHEMBL9016500 | 0.81 | PPARG (0.41) | KMT2ALMNAMAPTNPC1RAB9A | |
| SCHEMBL9016461 | 0.80 | PPARG (0.36) | KMT2ALMNANPC1HTTGAA | |
| SCHEMBL7825213 | 0.80 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL9016513 | 0.78 | ADAMTS4 (0.37) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL9016533 | 0.76 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL28577071 | 0.73 | LMNA (0.59) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL829966 | 0.73 | LMNA (0.59) | MEN1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL11711497 | 0.72 | MEN1 (0.54) | MEN1KMT2ALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |