SCHEMBL9016948

SCHEMBL9016948

O=C(O)C1CCCC12C(=O)OC2=O

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.31
CYP3A4 P08684 3/20 0.31
MAPK1 P28482 3/20 0.31
LMNA P02545 3/20 0.31
HIF1A Q16665 2/20 0.31
CYP1A2 P05177 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
TSHR P16473 2/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
TFPI2 P48307 1/20 0.31
PPP5C P53041 1/20 0.31
PPP2CA P67775 1/20 0.31
PPP1CA P62136 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231600 0.94 LMNA (0.36) LMNATSHR
SCHEMBL3157012 0.94 LMNA (0.36) LMNATSHR
SCHEMBL643447 0.72 TP53 (0.32) TP53CYP3A4MAPK1LMNAHIF1A
SCHEMBL11755338 0.67 TP53 (0.31) TP53CYP3A4MAPK1LMNAHIF1A
SCHEMBL25601715 0.66 SLC1A2 (0.35) LMNACYP1A2SMN1; SMN2TSHRKDM4E
SCHEMBL31332648 0.66 SLC1A2 (0.35) LMNACYP1A2SMN1; SMN2TSHRKDM4E
SCHEMBL6221971 0.66 SLC1A2 (0.35) LMNACYP1A2SMN1; SMN2TSHRMTOR
SCHEMBL23364672 0.64 SLC1A2 (0.42) TP53MAPK1LMNAHIF1ACYP1A2
SCHEMBL20488174 0.64 SLC1A2 (0.34) LMNACYP1A2SMN1; SMN2TSHRMTOR
SCHEMBL988351 0.64 GRM4 (0.38) LMNACYP1A2TSHRKDM4EMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2877541-A1 WATERBORNE COATINGS The Sherwin-Williams Company (US) 2015-06-03 EP disclosed
WO-2014018843-A1 WATERBORNE COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 2014-01-30 WO disclosed
US-5516579-A RIGID COMPOSITE GENERAL ELECTRIC COMPANY (US) 1996-05-14 US disclosed
US-5322905-A Heat, oxidation and radiation resistant GENERAL ELECTRIC COMPANY (US) 1994-06-21 US disclosed
US-5272206-A Vulcanized blends of thermoplastic elastomers and EPDM rubber and method for making GENERAL ELECTRIC COMPANY (US) 1993-12-21 US disclosed
EP-0215808-B1 ELASTOMERIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-04-07 EP disclosed
EP-0535163-A1 VULCANIZED BLENDS OF THERMOPLASTIC ELASTOMERS AND EPDM RUBBER AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 1993-04-07 EP disclosed
EP-0191283-B1 ELASTOMERIC COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-03-24 EP disclosed
WO-1992018570-A1 VULCANIZED BLENDS OF THERMOPLASTIC ELASTOMERS AND EPDM RUBBER AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 1992-10-29 WO disclosed
EP-0180148-B1 MODIFIED THERMOPLASTIC COPOLYETHERIMIDE ESTER ELASTOMERS GENERAL ELECTRIC COMPANY (US) 1991-03-20 EP disclosed
WO-1986004071-A1 THERMOPLASTIC POLYETHERIMIDE ESTER ELASTOMERS GENERAL ELECTRIC COMPANY (US) 1986-07-17 WO disclosed
US-4598117-A MOLDING MATERIALS, POLYIMIDES; POLYETHERS, POLYESTERS, IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1986-07-01 US disclosed
US-4594377-A From low molecular weight diol, dicarboxylic acid and polyoxyalkylene diimide diacid GENERAL ELECTRIC COMPANY (US) 1986-06-10 US disclosed
EP-0180148-A2 Modified thermoplastic copolyetherimide ester elastomers GENERAL ELECTRIC COMPANY (US) 1986-05-07 EP disclosed
EP-0180149-A2 High molecular weight diimide diacids and diimide diesters of tricarboxylic anhydrides GENERAL ELECTRIC COMPANY (US) 1986-05-07 EP disclosed
EP-0179470-A2 Thermoplastic polyetherimide ester elastomers GENERAL ELECTRIC COMPANY (US) 1986-04-30 EP disclosed
US-4556688-A STRESS-STRAIN RESISTANT, LOW TENSILE SET, HIGH MELTING POINT, HIGH-STRENGTH, TOUGHNESS, FLEXIBILITY; DIOL, DICARBOXYLIC ACID, POLYOXYALKYLENEDIAMINE, TRICARBOXYLIC ACID GENERAL ELECTRIC COMPANY (US) 1985-12-03 US disclosed
US-4556705-A Thermoplastic polyetherimide ester elastomers GENERAL ELECTRIC COMPANY (US) 1985-12-03 US disclosed
US-4552950-A Polyetherimide esters GENERAL ELECTRIC COMPANY (US) 1985-11-12 US disclosed
US-4544734-A FLEXIBILITY GENERAL ELECTRIC COMPANY (US) 1985-10-01 US disclosed